ABSTRACT
Background: The presence of mass in the nose may seem to be a simple problem; however it raises several issues about the differential diagnosis. The aim of this study is to evaluate the histological profile of nasal masses in the environment. Methods: This is a retrospective and prospective study of nasal masses during a period of five years of patients presenting to the clinician in our hospital. Results: A total of 90 patients were analysed age ranging from 3 to 80 years. Majority of patients were in the second decade. Sex wise distribution showed a male to female ratio of 2.2:1. The main presenting symptom was nasal obstruction seen in 53.30% patients, while proptosis was seen only in malignant lesion. Among a total of 90 lesions in the nasal cavity 81.1% were benign, 15.5 % were malignant and 3.3% were inadequate sample The commonest non neoplastic lesion was nasal polyp which comprised about 83.33% followed by rhinoscleroma, while the commonest benign neoplastic lesion was papilloma and comprised about 42.10% and squamous cell carcinoma was the most common malignant neoplastic lesion in the nasal cavity and comprised about 42.85%. Most patients with benign lesion were in the second decade. Malignant lesions occurred mainly after fifth decade, while inadequacy of sample was seen in the second decade. Conclusion: Males are more commonly affected then females. Nasal obstruction is the commonest symptom Simple inflammatory nasal polyp is still the commonest histological pattern seen while papilloma being the most common benign lesion and squamous cell carcinoma the most common malignant lesion.
ABSTRACT
Background: Scrape cytology is quick method to know difference between benign & malignant lesions hence aid in early diagnosis. This can in turn lead to quick management even intra operatively. This diagnostic discipline has arisen in parallel but much before contemporary histology. Aims & Objective: (1) To establish scrape cytology techniques as a routine procedure for diagnosis of surgical specimen; (2) To evaluate the diagnostic accuracy of scrape cytological techniques in the diagnosis; (3) To study the merits and pitfalls of scrape cytological techniques in the diagnosis; (4) Correlations of findings of scrape cytology with histopathological findings. Materials and Methods: This was a prospective study of 100 surgical specimens submitted in Department of Pathology, MGM Medical College, Indore. Smears obtained were stained with Papanicolaou Stain & studied. Results: Out of total 33 benign lesions, 31 (94%) were diagnosed correctly and 1 (3%) was false negative & 1 (3%) was not correlating well with histology. Out of total 67 malignant lesions 60 (89.6%) were diagnosed correctly, 2 (3.0%) were false negative and 5 (7.4%) did not correlated with histology. Conclusion: Scrape cytology is rapid technique for diagnosis & can be utilized in place of frozen section as well as adjuvant to histological diagnosis.
ABSTRACT
Background: Imprint smear is simple and rapid technique for tissue diagnosis. Imprint is a touch preparation in which tissue is touched on the slide and it leaves behind its imprint in the form of cells on glass slide; studies are made after proper staining. Aims & Objective: (1) To evaluate utility of imprint smears as diagnostic modality; (2) To study the merits and pitfalls of imprint smears techniques in the diagnosis; (3) To correlate the findings of imprint smears with histopathological findings. Materials and Methods: This was a prospective study of 100 surgical specimens submitted in Department of Pathology, MGM Medical College, Indore. Smears obtained were stained with Papanicolaou Stain & studied. Results: Out of total 35 benign lesions, 32(91.4%) were diagnosed correctly and 03(8.6) was false negative. Out of total 65 malignant lesions 58 (89.2%) were diagnosed correctly, 07 (10.8%) were false negative. Conclusion: Imprint smear is rapid technique for diagnosis & can be utilized for adjuvant to histological diagnosis.